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Is nifedipine sustained-release tablets a type of nitrate drug?

May 11, 2023 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Nifedipine sustained-release tablets generally do not belong to the class of nitrate drugs. Nifedipine sustained-release tablets are a type of calcium ion influx blocker and are not classified as nitrates. After entering the body, they inhibit the influx of calcium ions into cells, thereby exerting a vasodilatory effect. This helps reduce resistance in the coronary and peripheral blood vessels and increases blood flow.

Nifedipine sustained-release tablets generally do not belong to the class of nitrate drugs. The details are as follows:

Nitrate drugs typically exert vasodilatory effects. After entering the body, they inhibit platelet aggregation and adhesion in the bloodstream, thereby helping to prevent thrombus formation. Common nitrate medications include nitroglycerin tablets, isosorbide dinitrate tablets, and isosorbide mononitrate sustained-release tablets. These are clinically used primarily for treating conditions such as coronary atherosclerotic heart disease and angina pectoris. Nifedipine sustained-release tablets, on the other hand, belong to a class of calcium channel blockers that inhibit calcium ion influx into cells. By blocking calcium entry, they promote vasodilation, reduce resistance in the coronary and peripheral blood vessels, and increase blood flow. Clinically, nifedipine sustained-release tablets are commonly used to treat hypertension and angina pectoris.

It is recommended to choose either nifedipine sustained-release tablets or nitrate drugs such as nitroglycerin tablets or isosorbide dinitrate tablets under a physician's guidance based on specific medical conditions, to avoid potential adverse reactions.


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