What is hemiatrophy and how should it be managed?
May 15, 2023
Source: Cainiu Health
Dr. Yang Jun
Introduction
Hemiatrophy may be associated with genetic factors, protein abnormalities, environmental factors, and can be managed through daily care, physical methods, and drug therapy. Some cases of hemiatrophy are related to genetic factors. If there are abnormalities in genes such as MAPT, GRN, or C9orf72 in direct relatives,
Hemiatrophy may be associated with genetic factors, protein abnormalities, environmental factors, and other causes. It can be managed through daily care, physical therapies, and medication. A detailed analysis is as follows:
1. Genetic factors
Some cases of hemiatrophy are related to genetic factors. Abnormalities in genes such as MAPT, GRN, or C9orf72 in direct family members may lead to hemiatrophy. Patients should maintain a balanced diet and engage in appropriate exercise to strengthen their constitution and help alleviate symptoms.
2. Protein abnormalities
Abnormal Tau and TDP-43 proteins are present in the brain tissue of patients with hemiatrophy, which may lead to neuronal death and neurodegeneration. Under medical guidance, patients may use medications such as dobutamine hydrochloride injection or alprazolam tablets for treatment.
3. Environmental factors
Long-term exposure to harmful substances such as certain chemicals, heavy metals, or pesticides may increase the risk of developing hemiatrophy. Patients should avoid harmful environments and, under medical supervision, undergo cognitive training—including memory exercises and problem-solving tasks—which can help improve cognitive function and attention.
In addition to the above common causes, hemiatrophy may also be associated with chronic inflammation, oxidative stress, and lack of neurotrophic support. Patients should receive standardized treatment under medical supervision and must not use medications indiscriminately.
