What does it mean when white blood cells decrease and C-reactive protein increases, and what should be done?
May 30, 2023
Source: Cainiu Health
Dr. Zhang Heyang
Introduction
In general, a decrease in white blood cells accompanied by elevated C-reactive protein may be caused by conditions such as rheumatoid arthritis, aplastic anemia, or systemic lupus erythematosus, and treatment should be tailored according to the specific underlying cause. Besides these conditions, other possible causes include cytomegalovirus infection, chickenpox, measles, and others. Patients are advised to seek timely medical attention at a正规 hospital.
Generally, a decrease in white blood cells accompanied by an elevated C-reactive protein (CRP) level may be caused by conditions such as rheumatoid arthritis, aplastic anemia, or systemic lupus erythematosus. Treatment should be tailored according to the specific underlying cause. Details are as follows:
1. Rheumatoid Arthritis
Rheumatoid arthritis is characterized by multiple, symmetric, and invasive inflammations primarily affecting small joints in the hands and feet, often due to factors such as sex hormones and decreased lysosomal membrane stability. Laboratory tests commonly reveal reduced white blood cell counts and elevated CRP levels. Patients are advised to follow medical instructions and use medications such as dexamethasone acetate tablets and azathioprine tablets for treatment.
2. Aplastic Anemia
Aplastic anemia is a syndrome characterized by reduced bone marrow hematopoietic tissue and impaired hematopoietic function, leading to pancytopenia in peripheral blood. Laboratory findings frequently show decreased white blood cell counts and increased CRP levels. Common symptoms include subcutaneous bleeding, palpitations, easy fatigue, low immunity, increased respiratory and heart rates, loss of appetite, and abdominal discomfort. In most cases, patients can follow medical advice to adjust their diet and take medications such as mycophenolate mofetil capsules and cyclophosphamide tablets.
3. Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease associated with various factors including genetics, sex hormones, and infections. Clinical manifestations may include annular rashes, neuropsychiatric changes, and anemia. Due to immune system dysfunction, the aforementioned laboratory abnormalities may occur. Patients are recommended to take medications such as methylprednisolone tablets and prednisone acetate tablets as directed by their physicians.
Besides the above-mentioned causes, other conditions such as cytomegalovirus infection, chickenpox, and measles may also lead to similar findings. Patients are advised to seek timely medical evaluation at a qualified healthcare facility.
