What causes a decrease in white blood cell count?

Feb 27, 2023 Source: Cainiu Health
Dr. Zhang Heyang
Introduction
A decrease in white blood cell count is generally classified as either physiological or pathological. Physiological decreases may occur, for example, in women during menstruation, while pathological causes may include conditions such as typhoid fever, the common cold, or aplastic anemia. Appropriate treatment should be actively pursued depending on the specific cause. In addition, a reduced white blood cell count may also result from taking certain medications orally or prolonged exposure to radioactive substances.

Leukocyte count reduction can generally be divided into physiological and pathological causes. Physiological decreases may occur in women during menstruation, while pathological causes may include conditions such as typhoid fever, common cold, or aplastic anemia. Appropriate treatment should be actively pursued based on the specific cause.

I. Physiological Causes

A decrease in leukocyte count may occur during a woman's menstrual period, due to excessive fatigue, or from long-term irregular eating habits. In most cases, the leukocyte count returns gradually to normal after eliminating the underlying cause, without requiring special treatment.

II. Pathological Causes

1. Common Cold

When the body's immunity is reduced, it becomes more susceptible to viral infections, leading to the common cold, which may result in decreased leukocyte count. Symptoms may also include fever and generalized body aches. Patients should seek timely medical evaluation and, under a doctor’s guidance, undergo antiviral treatment, such as with Ganmaoling granules or Ribavirin granules.

2. Aplastic Anemia

In patients with aplastic anemia, blood tests typically reveal a reduced white blood cell count. Symptoms may include dizziness and angina pectoris. Under medical supervision, medications such as deferasirox dispersible tablets or danazol capsules may be used. In severe cases, hematopoietic stem cell transplantation may be recommended.

Besides the above, decreased leukocyte count may also be caused by taking certain medications or prolonged exposure to radioactive substances.


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