Is a quantitative test result of 2.48E+4 for hepatitis B virus DNA severe?
May 30, 2023
Source: Cainiu Health
Dr. Jiang Weimin
Introduction
The result of quantitative detection of hepatitis B virus nucleic acid is 2.48E+4, indicating a hepatitis B virus load of 24,800 cps/ml. The normal value is less than 1,000 cps/ml, so this result suggests active viral replication and strong infectivity. If the individual is in the phase of infection, the condition is generally not severe; however, if chronic hepatitis B has already developed, the condition may be more serious.
The quantitative test result for hepatitis B virus (HBV) nucleic acid is 2.48E+4, indicating a viral load of 24,800 copies/ml (cps/ml). Since the normal value is less than 1,000 cps/ml, this suggests active HBV replication and strong infectivity. If the individual is in the phase of infection, the condition is generally not severe; however, if chronic hepatitis B has already developed, the condition is usually more serious. Specific details are as follows:
1. Not Severe
The value from the HBV nucleic acid quantitative test is directly proportional to the level of viral replication—higher values indicate more active replication and greater infectivity. However, this test alone does not reflect the severity of liver disease, which requires liver function tests for clarification. If liver function tests show only mild liver damage, it typically indicates the individual is in the infection phase and is a hepatitis B carrier. Such patients usually do not experience significant symptoms and their condition is generally not severe. Nevertheless, they should actively take antiviral medications as prescribed by a doctor to eliminate the virus. Commonly used medications include tenofovir disoproxil fumarate tablets and entecavir tablets.
2. Severe
If liver function tests reveal significant liver damage along with symptoms such as fatigue, loss of appetite, abdominal bloating, and dark urine, it usually indicates the development of chronic hepatitis B. In addition to taking antiviral medications as directed, patients often need hepatoprotective drugs such as ursodeoxycholic acid capsules or hepatic-protective tablets, as prescribed. Regular monitoring of liver function is essential to track disease progression and adjust treatment strategies promptly.
It is important to note that individuals with an HBV DNA level of 2.48E+4 should seek timely medical evaluation, including liver function tests, to determine disease stage and initiate appropriate treatment under medical supervision.
