How can someone develop lacunar infarction without the three highs (hypertension, hyperlipidemia, and hyperglycemia)?

　　"Lacunar infarction" refers to lacunar cerebral infarction. Even without the three major risk factors (hypertension, hyperlipidemia, and hyperglycemia), lacunar infarction may still be associated with age, obesity, genetic factors, and others. During treatment, medication therapy can be selected under medical guidance. Specific details are analyzed as follows:

　　1. Age factor

　　As age increases, small arterial blood vessels gradually become occluded and hardened, impairing cerebral blood supply and leading to ischemic necrosis of brain tissue. At this point, even in the absence of the three major risk factors, lacunar cerebral infarction may still occur. To address this issue, medications can be used under a doctor's direction, such as clopidogrel hydrogen sulfate tablets or atorvastatin calcium tablets.

　　2. Obesity factor

　　Obesity increases blood viscosity, hinders blood circulation, and predisposes individuals to thrombus formation, thereby increasing the incidence of lacunar cerebral infarction. In such cases, it is recommended to use ticlopidine hydrochloride tablets or enteric-coated aspirin tablets as directed by a physician to improve the condition.

　　3. Genetic factors

　　If one or more family members have previously experienced lacunar cerebral infarction, the individual's risk of developing the condition significantly increases. After diagnosis, drug management under medical supervision is advised, using medications such as Shuxuening tablets or vinpocetine tablets.

　　In addition to the above-mentioned causes, lacunar infarction may also be related to conditions such as thrombocythemia, arteritis, or congenital vascular malformations. Once the cause is identified, appropriate management is recommended. Maintain adequate rest and pay attention to weight control in daily life.