Can I still have children after conization for CIN3?

Cervical intraepithelial neoplasia grade 3 (CIN3) is a severe abnormal change in cervical epithelial cells. If detected early and managed with prompt treatment and regular follow-up, it can usually be cured. However, if the disease reaches an advanced stage and becomes more severe, complete cure is generally not possible. It is recommended to seek timely medical care and actively undergo treatment under a doctor's guidance to control the disease progression and alleviate symptoms.

In general, high-grade cervical squamous intraepithelial lesions (CIN2 to CIN3) may be caused by factors such as long-term smoking, early onset of sexual activity, prolonged use of oral contraceptives, high-grade squamous cell changes, and persistent infection with high-risk types of HPV. Timely medical treatment is recommended. Patients are advised to maintain healthy sexual habits and undergo regular gynecological examinations.

CIN3 refers to cervical precancerous lesions and represents the most severe type of cervical intraepithelial neoplasia. Immediate surgical treatment is required upon diagnosis; earlier surgery helps control disease progression and reduces its risks. During treatment, patients should get adequate rest, maintain a balanced diet, and avoid resuming sexual intercourse too early to prevent an increased risk of cross-infection.

In general, "involvement of the gland" refers to CIN3 (cervical intraepithelial neoplasia grade 3) involving the glandular epithelium, which is categorized as a high-grade cervical lesion. CIN3 involving the gland indicates that cervical intraepithelial neoplasia has reached grade 3, representing the most advanced stage of precancerous changes. At this stage, there may already be concurrent glandular epithelial involvement. When CIN3 extends into the glands, it suggests that cervical neoplastic changes have progressed to an advanced precancerous state.

Generally speaking, there is no such thing as "CIN grade 11." CIN, or cervical intraepithelial neoplasia, is classified into three grades—CIN1, CIN2, and CIN3—representing mild, moderate, and severe abnormalities of the cervical epithelium, respectively. When determining treatment for CIN, doctors typically consider factors such as the grade of the lesion, the patient's age, and fertility plans.

"CIN3 with glandular involvement" generally refers to CIN3 extending into the cervical glands. This represents a special manifestation of CIN3, indicating that the precancerous changes have spread into the glandular epithelium of the cervix and are in an advanced stage of transformation, requiring more aggressive treatment. The severity of CIN3 with glandular involvement depends on the extent and degree of the lesion. Regular cervical cancer screening is essential for early detection and timely management of CIN3 with glandular involvement.

宫颈癌前病变三级并不是宫颈癌早期。宫颈癌前病变属于宫颈癌前的病变，还没有发展到宫颈癌，所以并不是宫颈癌的早期。宫颈癌前病变三个等级，分别为CIN1、CIN2、CIN3。一级病变和二级病变一般比较轻微，一般需要通过保守Treatment，部分可转为正常。

Cervicitis typically presents as mild epithelial hyperplasia and inflammatory infiltration of the cervix. There is an increased number of cells in the cervical epithelium, with cellular morphological changes and possibly uneven chromatin distribution in the nuclei. Cervical intraepithelial neoplasia (CIN) is a type of cervical disease classified into three grades—CIN1, CIN2, and CIN3—representing different degrees of lesion severity. It is characterized by marked epithelial cell proliferation and severe atypical hyperplasia of the epithelial cells.