Can a positive hepatitis A result turn negative?
Oct 18, 2023
Source: Cainiu Health
Dr. Lu Haiying
Introduction
In general, hepatitis A refers to hepatitis A virus infection. Whether a positive result for hepatitis A turns negative depends on the type of antibody present in the body. If it is IgM antibody, it usually becomes negative after treatment; if it is IgG antibody, it may remain positive. Patients experiencing discomfort symptoms are advised to seek timely medical attention at a hospital to avoid delaying diagnosis and treatment.
In general, hepatitis A refers to hepatitis A virus infection. Whether a positive result for hepatitis A turns negative depends on the type of antibody present in the body. If it is IgM antibody, it usually becomes negative after treatment; if it is IgG antibody, it may remain positive indefinitely. The specific analysis is as follows:
1. Yes (it can turn negative)
Hepatitis A patients typically develop two types of antibodies: IgM and IgG. Under normal circumstances, IgM antibodies become detectable within a few days after infection, indicating an active hepatitis A virus infection. With timely intervention and treatment, these antibodies gradually become negative after recovery.
2. No (it may not turn negative)
IgG antibodies usually appear positive 3–12 weeks after infection. In some individuals, these antibodies may become negative within 5–10 years, but in others, they may remain positive for life. However, IgG antibodies are protective and help prevent reinfection with the hepatitis A virus. Therefore, a positive IgG result is not a cause for concern.
If a patient experiences any symptoms or discomfort, it is recommended to seek medical attention at a hospital promptly to avoid delays in diagnosis and treatment.
