How to Interpret a Six-Hormone Panel Report for Polycystic Ovary Syndrome

Oct 26, 2023 Source: Cainiu Health
Dr. Zhao Xiaodong
Introduction
Polycystic refers to polycystic ovary syndrome (PCOS). The six-hormone test report evaluates PCOS based on indicators including follicle-stimulating hormone, luteinizing hormone, and testosterone. Follicle-stimulating hormone (FSH) is a glycoprotein hormone synthesized and secreted by the anterior pituitary gland, which promotes the development and maturation of ovarian follicles. Luteinizing hormone (LH) is a glycoprotein hormone secreted by the basophils of the anterior pituitary gland.

Polycystic refers to polycystic ovary syndrome (PCOS). Generally, the diagnosis of PCOS based on a six-hormone test report involves evaluating levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone. The specific analysis is as follows:

1. Follicle-stimulating hormone (FSH): FSH is a glycoprotein hormone synthesized and secreted by the anterior pituitary gland, which promotes the development and maturation of ovarian follicles.

2. Luteinizing hormone (LH): LH is a glycoprotein hormone secreted by the basophilic cells of the anterior pituitary gland, which helps promote follicular maturation and estrogen secretion. If the ratio of LH to FSH is more than twice the normal level, it may indicate polycystic ovary syndrome.

3. Testosterone: Testosterone is an androgen that promotes the development and maturation of male secondary sexual characteristics and maintains male reproductive organ function. In females, the normal range of testosterone is 0.7–3.1 nmol/L. If testosterone levels exceed this normal range and LH levels are higher than FSH levels, polycystic ovary syndrome may be present.

It should be noted that diagnosing polycystic ovary syndrome requires a comprehensive evaluation, including clinical symptoms and B-mode ultrasound findings.

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