Should metformin be continued after transplantation?
In general, transplantation usually refers to transferring specific cells, tissues, or organs to their corresponding locations in the body to help restore the anatomical structure and physiological function of damaged organs or tissues. Metformin refers to metformin hydrochloride tablets. If blood glucose control is inadequate after transplantation, it is recommended to continue taking metformin hydrochloride tablets to maintain stable blood glucose levels. The detailed explanation is as follows:
After transplantation, patients' hormone levels may change. These changes can sometimes affect insulin secretion and sensitivity, leading to fluctuations in blood glucose levels. Metformin hydrochloride is a commonly used antidiabetic medication that primarily lowers blood glucose by inhibiting hepatic glucose output, improving insulin sensitivity in peripheral tissues, and enhancing glucose uptake and utilization. Therefore, when post-transplant patients experience poor glycemic control, continuing metformin hydrochloride treatment helps maintain stable blood glucose levels and reduces adverse risks associated with hyperglycemia.
Routine blood glucose monitoring is necessary, and medication dosages should be adjusted according to medical advice to ensure stable blood glucose levels.