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Will melasma rebound after discontinuing Tranexamic Acid?

Sep 21, 2024 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Tranexamic acid tablets are commonly known as "Tuosaimin." In general, melasma may rebound after discontinuation of tranexamic acid tablets. The skin type, severity of melasma, and individual response to the medication vary among individuals. For those with mild melasma and better skin metabolism, the condition may not rebound immediately after stopping the drug, or the rebound may be less severe.

Tranexamic acid tablets are commonly known as "Tuosenmin." In general, melasma may rebound after discontinuation of tranexamic acid tablets. Different individuals have varying skin types, degrees of melasma severity, and responses to medication. For people with mild melasma and good skin metabolism, the condition may not rebound immediately or may only mildly recur after stopping the medication. However, for those with more severe melasma and additional triggering factors—such as prolonged sun exposure or endocrine disorders—the likelihood of rebound is higher.

If you wish to remove melasma, medical aesthetic treatments such as chemical peels, microneedling therapy, cryotherapy, intense pulsed light (IPL) photorejuvenation, and fractional laser therapy are available. It is recommended to consult at a reputable medical institution.

Procedure Name

Chemical Peel

Microneedling Therapy

Cryotherapy

Intense Pulsed Light (IPL)

Fractional Laser

Image Example

Procedure Overview

Causes shedding of pigment particles in the superficial skin layer and promotes collagen production

Micro-needles stimulate collagen production and promote cellular renewal

Lowers temperature to damage melanocytes and expel them from the body

Uses intense pulsed light to accelerate decomposition and metabolism of pigment cells

Laser energy breaks down melanin and facilitates its removal from the body

Indications

Mild melasma

Mild to moderate hereditary pigmentation

Mild to moderate hereditary pigmentation

Mild melasma

Moderate to severe melasma

Recovery Time

1–2 weeks

2–4 weeks

2–3 months

2–4 weeks

3–6 months

Duration of Effect

3–6 months

1–2 years

2–10 years

1–2 years

3–5 years

Reference Price

2,000–3,000 RMB per session

1,000–3,000 RMB per session

2,000–4,000 RMB per session

3,000–6,000 RMB per session

2,000–5,000 RMB per session

Advantages

1. High safety profile
2. Improves skin texture

1. Minimal irritation
2. Improves skin texture

1. Non-invasive and painless
2. Reduces hyperpigmentation

1. Noticeable results
2. Skin brightening effect

1. Effectively removes pigmentation
2. Broad applicability

Potential Risks

1. Hyperpigmentation
2. Skin damage

1. Minor bleeding and crusting
2. Pain

1. May cause pain
2. Pigment deposition

1. Skin burns
2. Photosensitivity reactions

1. Pain
2. Risk of infection

In daily life, it is recommended to pay attention to sun protection and consume foods rich in vitamin C and vitamin E, which can help fade melasma.

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