What causes small blisters on the hands?

Sep 24, 2024 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
In general, small blisters on the hands may be related to factors such as insect bites, burns, dyshidrotic eczema, allergic reactions, or tinea manuum (fungal infection of the hands). If discomfort occurs, it is recommended to seek medical attention promptly and follow a doctor's guidance regarding general treatments or medication. In daily life, one should maintain good hand hygiene, washing hands frequently before meals and after using the toilet, to prevent bacterial infections.

Generally, small blisters on the hands may be related to factors such as insect bites, burns, dyshidrotic eczema, allergic reactions, or tinea manuum (fungal infection of the hands). If discomfort occurs, it is advisable to seek medical attention promptly. Specific causes are analyzed as follows:

1. Insect bites

After being bitten by insects on the hand, local inflammatory reactions may occur, leading to the formation of small blisters. Clean the affected area with mild soapy water, then disinfect with iodophor or alcohol.

2. Burns

If the skin on the hand is scalded by hot water, fluid may accumulate beneath the damaged tissue, forming blisters. It is recommended to immediately rinse the burned area under gently flowing cool water for 15–30 minutes to reduce local temperature and alleviate injury and pain.

3. Dyshidrotic eczema (sweat blister rash)

When the hands remain in a moist and warm environment for prolonged periods, dyshidrotic eczema may develop, causing sweat to be trapped under the skin and resulting in small blisters accompanied by symptoms such as itching and peeling. Treatment may include medications prescribed by a doctor, such as halometasone cream, mometasone furoate cream, or calamine lotion.

4. Allergic reaction

When the skin on the hands comes into contact with allergens such as pollen or dust, an allergic reaction may occur. The immune system in the skin becomes activated and releases inflammatory mediators, potentially causing blisters, redness, swelling, and itching. Medications such as compound dexamethasone cream, hydrocortisone butyrate cream, or erythromycin ointment should be used as directed by a physician.

5. Tinea manuum (hand fungus)

Poor hand hygiene over time can lead to fungal growth and infection, resulting in tinea manuum. Once fungi invade the skin, immune cells release inflammatory mediators, causing small blisters along with symptoms like itching and red patches. Treatment should follow medical advice and may include antifungal medications such as ketoconazole cream, clotrimazole cream, or itraconazole capsules.

In daily life, attention should be paid to hand hygiene—washing hands before meals and after using the toilet—to prevent bacterial infections.

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