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What are pearly penile papules in men, and how should they be managed?

Nov 05, 2024 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Unhealthy lifestyle habits in men may trigger immune system abnormalities, thereby affecting the normal growth and differentiation of skin cells, potentially leading to the development of pearly penile papules, often accompanied by symptoms such as recurrent infections and joint pain. It is recommended to treat under medical supervision using medications such as pidotimod oral solution, transfer factor injection, and Bacillus Calmette-Guérin (BCG) polysaccharide nucleic acid injection.

In general, pearly penile papules in males may be caused by physiological changes, poor hygiene habits, immune system abnormalities, skin inflammation, or genital herpes. If discomfort occurs, it is recommended to seek medical attention promptly. Specific analyses are as follows:

1. Physiological Changes

Hormonal fluctuations during male puberty and early adulthood may stimulate sebaceous gland activity, leading to the development of pearly penile papules. These usually do not cause significant discomfort and generally do not require special treatment.

2. Poor Hygiene Habits

Poor personal hygiene, such as neglecting cleanliness of the genital area, may lead to accumulation of smegma, which can irritate the skin and trigger the formation of pearly penile papules. It is recommended to maintain good personal hygiene to reduce smegma buildup and irritation.

3. Immune System Abnormalities

Unhealthy lifestyle habits in males may lead to immune system dysfunction, affecting normal skin cell growth and differentiation, potentially resulting in pearly penile papules. This condition is often accompanied by recurrent infections, joint pain, and other symptoms. Under medical supervision, medications such as pidotimod oral solution, transfer factor injection, and BCG polysaccharide nucleic acid injection may be used for treatment.

4. Skin Inflammation

If males neglect proper cleaning and care of the genital skin, skin inflammation may develop, potentially contributing to the formation of pearly penile papules. Symptoms may include itching and scaling. Under medical supervision, treatment may involve medications such as enteric-coated aspirin tablets, salsalate tablets, and sodium aminosalicylate enteric-coated tablets.

5. Genital Herpes

Genital herpes is commonly caused by the herpes simplex virus. When the virus replicates within skin cells and triggers inflammation or necrosis, it may lead to lesions resembling pearly penile papules. This condition is often accompanied by pain and itching. Treatment should follow medical advice and may include antiviral medications such as oseltamivir phosphate capsules, antiviral oral liquid, and acyclovir tablets.

In daily life, appropriate physical exercise can be beneficial to enhance physical strength and boost immune function.

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