What is the only effective medication for palmoplantar pustulosis?
Nov 14, 2024
Source: Cainiu Health
Dr. Liu Wenmin
Introduction
In general, palmoplantar pustulosis can be treated with medications such as halometasone cream, tapinarof ointment, acitretin capsules, methotrexate tablets, and adalimumab injection, as directed by a physician. Halometasone cream can suppress the function of T lymphocytes, reduce the production of cytokines, thereby modulating the immune system's attack on the body's own skin tissues and alleviating inflammatory responses in the skin.
Generally, palmoplantar pustulosis can be treated with medications such as Halometasone Cream, Tacrolimus Ointment, Acitretin Capsules, Methotrexate Tablets, and Adalimumab Injection, as directed by a physician. The specific explanations are as follows:
1. Halometasone Cream: Halometasone cream can inhibit the function of T lymphocytes and reduce the production of cytokines, thereby modulating the immune system's attack on the body's own skin tissues. It alleviates the inflammatory response in the skin and reduces redness and swelling of the pustules and surrounding skin.
2. Tacrolimus Ointment: The skin barrier is often impaired in patients with palmoplantar pustulosis. Tacrolimus increases the ceramide content in the stratum corneum, helping to restore the skin's barrier function. This reduces further damage from external irritants and supports the skin's natural moisturization and recovery.
3. Acitretin Capsules: Acitretin capsules have anti-inflammatory properties and can inhibit the activity of inflammatory cells and the production of inflammatory mediators. By regulating the balance of cytokines, it reduces the skin's inflammatory response and alleviates symptoms in patients with palmoplantar pustulosis.
4. Methotrexate Tablets: Methotrexate reduces the production of inflammatory mediators, thereby alleviating the skin's inflammatory response and helping control the progression of palmoplantar pustulosis.
5. Adalimumab Injection: Adalimumab can alter the local skin's immune microenvironment, reduce the activation and proliferation of T lymphocytes, and suppress the autoimmune response. It helps break the cycle of chronic inflammation in patients with palmoplantar pustulosis and alleviates the condition at its root.
Patients with palmoplantar pustulosis should keep the affected areas clean and avoid scratching to prevent infection or worsening of symptoms. In daily life, they should wear loose, soft, and breathable footwear and gloves to reduce friction.
