Can HPV become negative after a cervical conization procedure?

Nov 09, 2024 Source: Cainiu Health

Dr. Zhang Lu

Introduction

HPV refers to human papillomavirus. The patient's immune system can effectively eliminate the remaining human papillomavirus, which can usually become negative. However, if the human papillomavirus has integrated with the cervical epithelium, it typically cannot become negative. Cervical conization can remove the affected cervical tissue, which usually contains a large amount of human papillomavirus.

Generally, HPV refers to human papillomavirus. The patient's immune system can effectively eliminate residual human papillomavirus, which usually can become negative. However, if the human papillomavirus has combined with the cervical epithelium, it usually cannot become negative. Detailed analysis is as follows:

Cervical conization can remove the diseased cervical tissue, which typically contains a large amount of human papillomavirus. Therefore, after surgery, the amount of human papillomavirus in the patient's body will be significantly reduced, potentially achieving a negative result. However, different patients have varying physical conditions and immune systems. Some patients' immune systems can effectively eliminate the remaining human papillomavirus, thus achieving a negative result. After surgery, doctors may recommend that patients use medications such as interferon and anti-human papillomavirus biological protein for adjuvant therapy. These medications help inhibit viral replication, enhance immunity, and promote the clearance of human papillomavirus.

Because human papillomavirus can not only bind to the cervical epithelium but also to the vaginal and vaginal vault tissues, cervical conization may not completely eliminate all human papillomavirus. These residual viruses may prevent the human papillomavirus from becoming negative. Even if the human papillomavirus becomes negative after surgery, patients may still experience recurrence or re-infection due to decreased immunity, sexual activity, and other factors.

After cervical conization, patients need to undergo regular gynecological examinations to monitor the clearance of human papillomavirus and the recovery of cervical tissue. Additionally, patients should maintain good hygiene of the external genitalia, avoid high-risk behaviors, maintain a regular lifestyle, abstain from smoking and alcohol consumption, avoid spicy and irritating foods, exercise appropriately, and strengthen their physical resistance and immunity.

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What does CIN of the cervix mean?

Cervical CIN refers to cervical intraepithelial neoplasia, which is a manifestation of precancerous lesions of the cervix, typically associated with human papillomavirus (HPV) infection. Patients may experience symptoms such as increased vaginal discharge and contact bleeding. Individuals without symptoms may be monitored initially, while those with more severe lesions are advised to undergo cervical conization to reduce the risk of cancer progression and control disease development.

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What is a cervical conization procedure?

In general, cervical conization is a surgical procedure in the department of obstetrics and gynecology that involves removing a portion of the cervix. Cervical conization refers to the excision of a cone-shaped tissue from the cervix, including part of the cervical tissue and endocervical canal tissue. Currently, loop electrosurgical excision procedure (LEEP) and cold knife conization are commonly used surgical methods for cervical conization.

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How much does a cone biopsy of the cervix cost?

Under normal circumstances, the principle of cervical conization is to surgically remove a cone-shaped portion of the cervix to treat conditions such as cervical intraepithelial neoplasia. This procedure uses specialized instruments to precisely remove the diseased tissue while endeavoring to preserve the normal cervical structure and minimize impact on fertility. The general reference price for cervical conization ranges from 8,000 to 22,000 yuan per procedure.

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Is cervical conization a major surgery?

In general, cervical conization is not a major surgical procedure, but it does carry certain risks. If surgery is required, it is recommended to seek timely medical attention and undergo treatment under the guidance of a physician. Although cervical conization is not considered a major operation, it involves the removal of cervical tissue, which may affect the structure and function of the cervix, potentially impacting future pregnancies and childbirth.