What happens if you take ibuprofen sustained-release capsules on an empty stomach?
Dec 23, 2024
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Taking ibuprofen sustained-release capsules on an empty stomach may cause gastrointestinal discomfort, poor drug absorption, liver and kidney function damage, allergic reactions, and a drop in blood pressure. It is recommended to take ibuprofen sustained-release capsules after a meal or with food to reduce the impact on the gastric mucosa. At the same time, during the course of medication, closely monitor whether any adverse symptoms occur, and if they do, discontinue the medication promptly and consult a doctor.
Generally, taking ibuprofen sustained-release capsules on an empty stomach may cause gastrointestinal discomfort, poor drug absorption, liver and kidney function damage, allergic reactions, and decreased blood pressure. The specific details are as follows:
1. Gastrointestinal discomfort: When taking ibuprofen sustained-release capsules on an empty stomach, the medication may irritate the gastrointestinal mucosa, leading to excessive gastric acid secretion and causing symptoms such as nausea, vomiting, loss of appetite, and upper abdominal discomfort.
2. Poor drug absorption: In an empty stomach state, reduced gastric acid secretion may affect the absorption and utilization of the active ingredients in ibuprofen sustained-release capsules, resulting in the medication not achieving its intended therapeutic effect.
3. Liver and kidney function damage: Long-term and excessive use of ibuprofen sustained-release capsules on an empty stomach may burden the liver and kidneys, causing elevated transaminase levels and symptoms of kidney damage such as decreased urine output and edema.
4. Allergic reactions: Some individuals may be sensitive to certain components in ibuprofen sustained-release capsules. Taking the medication on an empty stomach might more easily trigger abnormal immune responses, such as skin redness, itching, and difficulty breathing.
5. Decreased blood pressure: Ibuprofen sustained-release capsules have the effect of dilating vascular smooth muscle and reducing peripheral resistance. In an empty stomach state, when the body is at a low blood sugar level, it may easily induce sympathetic nerve excitation, increasing heart rate and cardiac contractility, ultimately leading to decreased blood pressure.
It is recommended to take ibuprofen sustained-release capsules after a meal or with food to reduce the impact on the gastric mucosa. At the same time, closely monitor for any adverse symptoms during medication use, and if any occur, discontinue the medication promptly and consult a physician. Patients with gastric diseases such as gastric ulcers or gastric bleeding, as well as those with impaired liver or kidney function, should use ibuprofen sustained-release capsules cautiously under the guidance of a physician.
