Can Hepatitis B virus nucleic acid testing confirm the diagnosis?
Jan 25, 2025
Source: Cainiu Health
Dr. Gao Jun
Introduction
Hepatitis B virus nucleic acid testing can analyze viral load and activity, but cannot alone confirm whether there is a hepatitis B virus infection. Therefore, for suspected cases, comprehensive evaluation should also include tests such as the five-panel hepatitis B markers, complete blood count, and liver function tests. Once symptoms such as loss of appetite, nausea, or yellowing of the complexion appear, timely medical consultation and diagnosis are necessary.
Generally speaking, hepatitis B virus refers to the hepatitis B virus (HBV). Nucleic acid testing for HBV plays a certain role in detection but cannot provide a definitive diagnosis. If experiencing any discomfort, timely medical consultation and additional examinations are necessary. Detailed analysis is as follows:
Nucleic acid testing for HBV mainly analyzes the viral load and activity level by detecting HBV DNA, thus helping understand disease progression. However, this method alone can only serve as one diagnostic tool for HBV and cannot provide a conclusive diagnosis. Therefore, to determine whether there is HBV infection, other diagnostic methods should also be used, such as the five-item hepatitis B test (hepatitis B surface antigen, surface antibody, e antigen, e antibody, core antibody), routine blood test, and liver function tests. These examinations can confirm whether there is current or past HBV infection and determine the current infection status.
If symptoms such as poor appetite, nausea, or yellowish complexion are currently present, it is recommended to promptly complete the necessary examinations and receive targeted treatment based on the results. Additionally, after a confirmed HBV infection, appropriate preventive measures must be taken to avoid cross-infection.
