Does metformin extended-release tablets affect liver function?

Metformin sustained-release tablets, also known as metformin hydrochloride sustained-release tablets. In general, for most patients, metformin hydrochloride sustained-release tablets do not affect liver function; however, for patients with existing liver disease or hepatic insufficiency, they may impact liver function. Medication should be used under the guidance of a physician. Detailed analysis is as follows:

Metformin hydrochloride sustained-release tablets are a commonly used oral hypoglycemic agent, primarily indicated for the treatment of type 2 diabetes. It lowers blood glucose levels by inhibiting hepatic glucose production and increasing peripheral tissue sensitivity to insulin. For most patients, metformin hydrochloride sustained-release tablets have minimal effects on liver function and do not cause significant liver damage. Under normal usage, this medication can generally be safely used in diabetic patients without causing severe side effects to the liver.

However, caution should be exercised when prescribing metformin hydrochloride sustained-release tablets to patients with existing liver disease or hepatic insufficiency. Impaired liver function may lead to slower drug metabolism, increasing the risk of lactic acidosis, a serious adverse effect. Additionally, patients with abnormal liver function may experience drug accumulation during treatment with metformin hydrochloride sustained-release tablets, which could further impair liver function. Therefore, such patients should consult a physician before using metformin hydrochloride sustained-release tablets. The physician will assess whether the drug is appropriate and determine any necessary dosage adjustments.

During treatment with metformin sustained-release tablets, it is important to maintain healthy lifestyle habits and avoid behaviors that may加重 liver burden, such as alcohol consumption and excessive fatigue.