Can retained fetal products after fetal demise affect coagulation function?
Mar 17, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
Under normal circumstances, retained fetal tissue after fetal demise may affect coagulation function. If necessary, it is recommended to consult a physician. When the fetus stops developing and remains in the uterine cavity without timely intervention, the placenta may begin to dissolve. During this process, an enzyme called fibrinolytic enzyme may be released into the maternal bloodstream. This enzyme has anticoagulant properties.
Generally, fetal remnants from a missed miscarriage may affect coagulation function. If necessary, it is recommended to consult a physician for professional advice. Detailed analysis is as follows:
When fetal development ceases and the embryo remains retained in the uterine cavity without timely intervention, the placenta may begin to dissolve. During this process, a type of enzyme known as a dissolving enzyme may be released into the maternal bloodstream. This enzyme has anticoagulant properties and can affect the activity of coagulation factors and the production of fibrin, thereby impairing blood clotting ability and leading to reduced coagulation function.
In addition, residual fetal tissue from a missed miscarriage may trigger an inflammatory response in the mother. As foreign material remaining in the uterus, these remnants can stimulate the maternal immune system, prompting the release of inflammatory mediators and cytokines. These inflammatory factors may not only interfere with the repair and regeneration of the endometrium but also further disrupt the balance of the coagulation system. Depending on the type and severity of the inflammation, coagulation function may be either suppressed or overactivated.
Pregnant women should maintain healthy lifestyle habits, including balanced nutrition, moderate exercise, and sufficient rest, to enhance overall physical health and immunity.
