How many milliliters is 400 cc of donated blood?

Jun 24, 2025 Source: Cainiu Health
Dr. Liu Feng
Introduction
Donating 400 cc of blood is equivalent to donating 400 ml, as both units are exactly equal in volume. However, before donating blood, you should ensure adequate sleep and avoid donating on an empty stomach. Women should avoid donating blood three days before and after their menstrual period. If you have recently experienced symptoms such as cold, fever, or other discomfort, or if you suffer from infectious diseases, cardiovascular diseases, or other illnesses, you should not donate blood in order to ensure both the safety of blood donation and your own health.

Generally speaking, donating 400cc of blood equates to 400ml, as both units are completely equivalent in volume. The detailed explanation is as follows:

When indicating volume, 1cc and 1ml represent exactly the same volume size. Therefore, donating 400cc of blood is equivalent to donating 400ml. Under conditions that meet blood donation requirements and with a body capable of tolerating it, donating a moderate amount of 400ml blood not only helps clinical patients, but can also promote the donor's own blood metabolism to some extent. This is a standard blood donation volume used in many countries when organizing blood donation activities, and is considered a relatively safe amount for most healthy adults while also effectively helping patients in need of blood transfusions.

However, prior to donating blood, one should ensure adequate sleep and avoid donating on an empty stomach; women should avoid the three days before and after their menstrual period; if experiencing recent symptoms such as colds or fever, or if suffering from infectious diseases, cardiovascular diseases, or other conditions, one should not donate blood to ensure both the safety of the donation and personal health.

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