What is the normal range for jaundice?

Jul 10, 2025 Source: Cainiu Health
Dr. Shen Yonghua
Introduction
For newborns, bilirubin levels typically do not exceed 6 mg/dL within 24 hours of birth, 9 mg/dL within 48 hours, and 12 mg/dL within 72 hours. After 72 hours, full-term infants usually have bilirubin levels no higher than 15 mg/dL, while preterm infants generally do not exceed 18 mg/dL. These ranges are mostly indicative of physiological jaundice, caused by an immature liver metabolism, and typically resolves within two weeks.

Under normal circumstances, the reference values for jaundice vary among different populations. In newborns, the values change with age, while in adults, the standard total bilirubin level is 0.1-1.7 mg/dL. If concerned, it is recommended to seek medical advice in advance. Detailed analysis is as follows:

In newborns, bilirubin levels should not exceed 6 mg/dL within 24 hours after birth, 9 mg/dL within 48 hours, and 12 mg/dL within 72 hours. After 72 hours, full-term infants should not exceed 15 mg/dL and premature infants should not exceed 18 mg/dL. These ranges are generally considered physiological jaundice, caused by an immature liver metabolism system, and usually resolves within two weeks.

In adults, a total bilirubin level exceeding 1.7 mg/dL is considered abnormal, which may be caused by hepatitis, biliary obstruction, etc., often accompanied by yellowing of the skin and darkened urine. In newborns, elevated bilirubin levels beyond the corresponding reference values may be due to hemolysis or infection, and pathological jaundice should be considered.

If jaundice or abnormal bilirubin levels are detected, timely medical evaluation is necessary. In newborns, bilirubin levels should be closely monitored, while in adults, liver and biliary system issues should be investigated to avoid delays in treatment.

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