What is the normal range for neonatal jaundice?
Jul 11, 2025
Source: Cainiu Health
Dr. Shen Yonghua
Introduction
In most cases, jaundice appears 2-3 days after birth. If the bilirubin levels are within the normal range and the infant is feeding well, crying vigorously, and in good general condition, it is usually physiological jaundice. This condition results from the newborn's liver function being not yet fully developed, leading to a slower metabolism of bilirubin. It typically resolves naturally within 7-14 days and does not require special treatment.
Generally, the normal range of neonatal jaundice is divided according to the days after birth and gestational age. For full-term infants, the bilirubin level should not exceed 6 mg/dL within 24 hours after birth, 9 mg/dL within 48 hours, and 15 mg/dL after 72 hours. For preterm infants, bilirubin levels should not exceed 18 mg/dL after 72 hours. Detailed analysis is as follows:
Jaundice appearing on the 2nd or 3rd day after birth, with bilirubin levels within the normal range and accompanied by normal feeding, loud crying, and good mental status, is usually physiological jaundice. This condition results from the incomplete development of the newborn's liver and the relatively slow metabolism of bilirubin. It typically resolves naturally within 7 to 14 days and requires no special treatment.
If jaundice appears too early (within 24 hours after birth), if bilirubin levels exceed the normal range for the corresponding days, or if jaundice reappears after fading, it may indicate pathological jaundice. Common causes include maternal-fetal blood group incompatibility, infections, and abnormal biliary tract development. Prompt intervention is necessary, as it may otherwise affect the development of the nervous system.
When observing jaundice in newborns, changes in skin color should be closely monitored. If bilirubin levels are abnormal or accompanied by symptoms such as lethargy or refusal to feed, prompt medical examination is required to ensure the infant's health.
