What are the advantages and disadvantages of in vitro fertilization (IVF)?

Jul 15, 2025 Source: Cainiu Health
Dr. Zhou Xiaofeng
Introduction
The advantages of in vitro fertilization (IVF) generally include helping infertile couples achieve pregnancy, screening for genetic diseases, improving the success rate of conception, resolving specific fertility issues, and providing flexibility in timing of conception. The disadvantages typically involve high costs, a potentially painful process, less than 100% success rate, possible complications, and an increased risk of multiple pregnancies.

Generally, the advantages of in vitro fertilization (IVF) include helping infertile couples achieve pregnancy, screening for genetic diseases, increasing the success rate of conception, resolving specific fertility obstacles, and providing flexibility in choosing the timing of pregnancy. The disadvantages typically include high costs, discomfort during the process, less than 100% success rate, potential complications, and an increased risk of multiple pregnancies. A detailed analysis is as follows:

I. Advantages

1. Helping infertile couples achieve pregnancy: For couples who are unable to conceive naturally due to conditions such as fallopian tube blockage or oligoasthenospermia, IVF offers the possibility of having biological children through techniques such as in vitro fertilization and embryo transfer, fulfilling their desire to have offspring.

2. Screening for genetic diseases: Preimplantation genetic testing allows for genetic analysis of embryos, identifying certain hereditary diseases, reducing the likelihood of transferring embryos with genetic defects, and increasing the chances of having healthy children.

3. Increasing the success rate of conception: The fertilization process takes place in a controlled laboratory environment, allowing for optimized conditions for sperm and egg union and selection of high-quality embryos for transfer. Compared to natural conception, this may increase the pregnancy success rate for certain individuals.

4. Resolving specific fertility obstacles: For fertility issues such as endometriosis or immunological infertility that cannot be improved through conventional treatments, IVF can bypass some obstacles and directly promote fertilization and embryo implantation.

5. Providing flexibility in choosing the timing of pregnancy: High-quality embryos can be preserved through embryo freezing technology, allowing couples to choose an optimal time for pregnancy based on their personal circumstances. For example, individuals needing to delay pregnancy due to medical treatments can preserve their fertility potential.

II. Disadvantages

1. High costs: The entire IVF process includes multiple stages such as ovulation stimulation medications, medical tests, in vitro fertilization, and embryo transfer, which can accumulate to a significant expense. Some of these costs may not be covered by health insurance, causing financial strain for certain families.

2. Discomfort during the process: Ovulation stimulation often requires multiple injections, the egg retrieval process may cause pain and discomfort, and the post-embryo transfer phase also involves a period of physical adjustment, all of which can cause physical distress to women.

3. Success rate is not 100%: IVF success rates vary depending on factors such as age, egg and sperm quality, and uterine lining conditions. There are individual differences in success rates, and some couples may need multiple attempts to succeed, increasing both physical and emotional burdens.

4. Potential complications: Ovarian hyperstimulation syndrome (OHSS) may occur during ovulation stimulation, manifesting as abdominal bloating, ascites, and other symptoms; egg retrieval may carry risks such as bleeding or infection, potentially affecting women's health.

5. Increased risk of multiple pregnancies: To increase success rates, multiple embryos are sometimes transferred, which may lead to multiple pregnancies, increasing risks such as gestational hypertension, preterm birth, and fetal growth restriction, posing threats to maternal and fetal health.

When considering IVF, it is important to fully understand its advantages and disadvantages, make informed decisions based on personal financial and physical conditions, strictly follow medical advice during the process, closely monitor physical changes, and minimize risks.

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