What does it mean to have a thickened endometrium?

Aug 15, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, increased endometrial thickness may be caused by hormonal fluctuations during puberty, hormonal imbalances during the perimenopausal period, anovulatory dysfunctional uterine bleeding, endometrial polyps, or adenomyosis. It is recommended to seek timely medical attention, identify the underlying cause, and receive symptomatic treatment under a doctor's guidance. In daily life, it is important to maintain healthy lifestyle habits, avoid excessive fatigue, and reduce the intake of spicy or cold foods.

Generally, thickened endometrium may be caused by hormonal fluctuations during puberty, hormonal imbalances during the perimenopausal period, anovulatory dysfunctional uterine bleeding, endometrial polyps, or adenomyosis. It is recommended to seek timely medical consultation to determine the exact cause and receive appropriate treatment under a doctor's guidance. Detailed explanations are as follows:

1. Hormonal fluctuations during puberty: During puberty, ovarian function is not yet mature, and estrogen secretion is unstable. Continuous stimulation of the endometrium can lead to endometrial hyperplasia, often manifesting as irregular menstrual cycles. No specific treatment is required; as ovarian function gradually matures with age, hormone levels stabilize, and endometrial thickness returns to normal. During this time, maintaining a regular sleep schedule, avoiding late nights, and reducing hormonal fluctuations are recommended.

2. Hormonal imbalances during the perimenopausal period: Ovarian function declines during the perimenopausal period, causing irregular and reduced estrogen secretion and insufficient progesterone production. The lack of progesterone opposition leads to persistent endometrial proliferation and abnormal thickness. Regular monitoring of endometrial thickness and hormone levels is necessary, along with maintaining emotional stability and avoiding anxiety.

3. Anovulatory dysfunctional uterine bleeding: Long-term anovulation prevents normal progesterone secretion, resulting in continuous estrogen-induced endometrial proliferation, often accompanied by heavy menstrual bleeding and prolonged menstrual periods. Patients should follow medical advice to use hormonal medications such as dydrogesterone tablets, progesterone capsules, or norethisterone tablets to regulate hormone levels and promote endometrial shedding.

4. Endometrial polyps: Localized excessive endometrial growth forms polyps, increasing overall endometrial thickness and often accompanied by abnormal uterine bleeding. Small polyps can be managed with medications such as levonorgestrel-releasing intrauterine systems, drospirenone-ethinyl estradiol tablets, or desogestrel-ethinyl estradiol tablets, as directed by a physician, to inhibit polyp growth.

5. Adenomyosis: Endometrial tissue invades the uterine muscle layer, leading to an enlarged uterus and thickened endometrium, often accompanied by dysmenorrhea and increased menstrual flow. Patients should follow medical advice to use medications such as triptolide capsules, danazol capsules, or leuprolide acetate microspheres to alleviate symptoms and reduce endometrial proliferation.

Maintaining healthy lifestyle habits in daily life is important, including avoiding excessive fatigue and reducing intake of spicy or cold foods. Menstrual hygiene should be emphasized, and strenuous exercise during menstruation should be avoided. Regular gynecological checkups are necessary to detect and address endometrial abnormalities promptly, thereby maintaining reproductive health.

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