Is a male high-risk HPV18 positive result serious?

Generally, the severity of a male testing positive for high-risk HPV18 depends on whether genital lesions are present and the type of lesion. If there are no obvious abnormalities and the immune system is functioning normally, the condition is relatively manageable. However, if genital warts or high-grade intraepithelial lesions are detected, prompt medical attention is required. If concerned, it is recommended to seek medical advice early. Detailed analysis is as follows:

If a man infected with HPV18 shows no genital abnormalities—such as redness, swelling, or wart-like growths—and has a healthy immune system, the virus may be naturally cleared by the immune system within 1–2 years. Regular monitoring during this period is sufficient, and the infection is unlikely to pose significant health risks in the short term; however, maintaining strong immunity remains important.

If wart-like growths appear on the genital area, or if pathological examination reveals high-grade intraepithelial lesions, immediate attention is necessary. HPV18 is a high-risk strain, and long-term persistent infection may increase the risk of malignant conditions such as penile cancer and anal cancer. The presence of lesions indicates that the virus has already caused tissue damage, and standardized treatment should be initiated promptly to prevent further progression.

Upon detection of a high-risk HPV18 positive result in males, timely medical consultation is essential, including thorough genital examination and necessary pathological testing.