Can Ganlixin and Bicyclol tablets be taken at the same time?

Nov 07, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Both have hepatoprotective effects, with different mechanisms and no obvious interaction. For elevated transaminase levels caused by drug-induced liver injury, chronic hepatitis, etc., they may be used concomitantly after physician evaluation. Combination therapy can reduce liver inflammation and promote hepatocyte repair through different pathways, thereby improving liver function indicators more effectively and facilitating recovery.

Ganlixin likely refers to diammonium glycyrrhizinate and sodium chloride injection. Under normal circumstances, diammonium glycyrrhizinate and sodium chloride injection and bicyclol tablets may be used concurrently when there is a clinical need for liver injury treatment and no contraindications to the medications. However, they should not be used together if there is no corresponding indication or if the patient has allergies or severe organ diseases. If in doubt, it is recommended to consult a healthcare provider in advance. Detailed analysis is as follows:

Both agents have hepatoprotective effects, with different mechanisms of action and no significant interactions. For elevated transaminase levels caused by drug-induced liver injury, chronic hepatitis, and similar conditions, they may be used together after physician evaluation. Combination therapy can reduce liver inflammation and promote hepatocyte repair through different pathways, thereby more effectively improving liver function parameters and facilitating recovery.

However, if there is no liver injury-related indication—for instance, if the medications are being considered only for routine health maintenance or treatment of unrelated conditions—concurrent use is unnecessary, as excessive medication may increase metabolic burden on the body. Additionally, simultaneous use is contraindicated in patients allergic to any component of either drug or those with severe renal insufficiency, heart failure, or similar serious conditions, to avoid triggering allergic reactions or worsening existing illnesses.

Before using both medications together, patients should inform their doctor of their medical history and current medication use; the physician will determine whether combination therapy is appropriate. Dosage and duration must strictly follow medical instructions and should not be adjusted independently.

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