Is it normal to get menstruation during the course of taking dydrogesterone tablets?

Nov 14, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, dydrogesterone tablets are a progestin medication. Whether menstrual bleeding during dydrogesterone use is normal depends on the purpose of treatment and the characteristics of the bleeding, and should be evaluated accordingly. If abnormal bleeding occurs, medical advice should be sought promptly. The medication should be taken as prescribed by the doctor in terms of dosage and timing; do not discontinue or adjust the dose without consultation. Maintain good external genital hygiene by washing with warm water.

Generally, dydrogesterone tablets are a type of progestin medication. Whether menstrual bleeding during the use of dydrogesterone is normal depends on the purpose of medication and characteristics of the bleeding. If abnormal bleeding occurs, it is recommended to seek medical attention promptly. The detailed analysis is as follows:

If dydrogesterone is taken to regulate the menstrual cycle, and the bleeding occurs at a time consistent with the expected menstrual period, with blood loss and duration similar to a regular period, and without significant abdominal pain or unusual clots, this situation is considered normal. The drug works by supplementing progesterone, causing the endometrium to shed and simulating a natural menstrual process. In this case, the bleeding reflects the intended therapeutic effect of the medication and does not require excessive concern.

If dydrogesterone is being used for maintaining pregnancy or treating luteal phase deficiency, vaginal bleeding during treatment—especially if irregular, heavy, or accompanied by abdominal pain—is abnormal. This may indicate that the underlying condition is not adequately controlled or that other factors are involved. Prompt medical evaluation is necessary to identify the cause and prevent delays in appropriate management.

In daily life, patients should take the medication exactly as prescribed by their doctor, including correct dosage and timing, and should not stop or adjust the dose without medical advice. Maintain good external genital hygiene by washing with warm water and frequently changing cotton underwear to prevent infection. Follow a light, nutritious diet rich in protein and vitamins, and avoid spicy or irritating foods. Ensure adequate rest, avoid strenuous exercise and excessive fatigue, maintain emotional stability, closely monitor and record any bleeding patterns, and provide detailed information to healthcare providers during consultations.

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