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Can Zhizhu Kuanzhong Capsules treat depression and anxiety?

Nov 17, 2025 Source: Cainiu Health
Dr. Zhang Baohua
Introduction
Zhi Zhu Kuan Zhong Capsules cannot treat depression or anxiety. This medication is a gastrointestinal agent whose primary functions are to strengthen the spleen, regulate the stomach, promote qi circulation, and relieve abdominal fullness. It does not have pharmacological effects against depression or anxiety and should not be used for treating such mental or psychological conditions. If symptoms of depression or anxiety occur, it is recommended to seek medical attention promptly for proper diagnosis. The main ingredients of Zhi Zhu Kuan Zhong Capsules include Atractylodes macrocephala, Aurantium fructus (Immature Bitter Orange), Bupleurum, and others.

Zhizhu Kuanzhong Capsules are not effective for treating depression or anxiety. This medication is a gastrointestinal drug whose primary functions are to strengthen the spleen, regulate stomach function, and relieve abdominal fullness and distension. It does not possess pharmacological effects against depression or anxiety and should not be used to treat such mental health conditions. If symptoms of depression or anxiety occur, it is recommended to seek medical attention promptly for proper diagnosis.

The main ingredients of Zhizhu Kuanzhong Capsules include Atractylodes macrocephala (Baizhu), Aurantium fructus (Zhishi), Bupleurum (Chaihu), and Hawthorn (Shanzha). Clinically, it is commonly used to treat stomach fullness caused by spleen deficiency and qi stagnation, with symptoms such as vomiting, acid reflux, poor appetite, and heartburn. It targets gastrointestinal functional disorders and is unrelated to the pathological mechanisms of depression or anxiety.

Depression and anxiety are mental health disorders that require professional psychological interventions or specific anti-anxiety and antidepressant medications. Their therapeutic targets involve balancing neurotransmitters in the central nervous system. Zhizhu Kuanzhong Capsules do not act on these targets and therefore cannot alleviate core symptoms such as low mood or anxious distress.

Zhizhu Kuanzhong Capsules should be taken strictly according to their indicated conditions to avoid inappropriate use. If both digestive discomfort and emotional issues are present, each condition should be treated appropriately and separately. Maintaining regular作息 (daily routines) and a light diet can help improve both physical and mental well-being.

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