What are the medications for depression?

Generally, depression is a mental disorder caused by various factors such as neurotransmitter imbalances. Common symptoms include low mood and reduced interest. Patients may take medications such as sertraline hydrochloride tablets, escitalopram oxalate tablets, mirtazapine tablets, venlafaxine hydrochloride sustained-release capsules, and duloxetine enteric-coated capsules under medical guidance. A detailed analysis is as follows:

1. Sertraline Hydrochloride Tablets

This medication belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It works by inhibiting the reuptake of serotonin at the presynaptic membrane, thereby increasing serotonin concentration in the synaptic cleft and improving depressive mood. It is suitable for all types of depression and particularly appropriate for patients with comorbid anxiety.

2. Escitalopram Oxalate Tablets

A highly selective serotonin reuptake inhibitor with strong affinity for serotonin transporters, it precisely regulates serotonin levels and alleviates depressive symptoms. The drug has a relatively fast onset of action and mild side effects, making it suitable for both adult and adolescent patients with depression.

3. Mirtazapine Tablets

Mirtazapine has a dual mechanism of action: it not only inhibits the reuptake of norepinephrine and serotonin but also antagonizes specific receptors. This helps improve mood while simultaneously relieving associated symptoms such as insomnia and loss of appetite. It is especially suitable for patients with depression accompanied by significant physical symptoms.

4. Venlafaxine Hydrochloride Sustained-Release Capsules

This drug is a serotonin-norepinephrine reuptake inhibitor (SNRI) that increases the concentrations of both neurotransmitters, comprehensively improving depressive mood and physical discomfort. The sustained-release formulation maintains stable blood drug levels, reduces dosing frequency, and enhances patient compliance.

5. Duloxetine Enteric-Coated Capsules

Duloxetine functions by inhibiting the reuptake of serotonin and norepinephrine. It is particularly effective for patients with depression accompanied by chronic pain, as it can simultaneously alleviate emotional distress and physical pain. The enteric-coated formulation minimizes gastrointestinal irritation.

Antidepressants must be used under the supervision of a physician; self-purchasing, self-administration, or dose adjustments are not recommended. During treatment, monitor bodily reactions closely and promptly inform your doctor of any adverse effects such as nausea or dizziness. Combining medication with psychotherapy, maintaining regular sleep patterns, and adopting a healthy diet will further support recovery.