Can erythromycin ointment be used for red, swollen, and itchy eyelids?
In general, whether erythromycin ointment can be used for red, swollen, and itchy eyelids depends on the underlying cause. The specific analysis is as follows:

When redness, swelling, and itching of the eyelids are caused by bacterial infections—such as blepharitis or early-stage styes—erythromycin ointment is usually appropriate. These conditions are often accompanied by local redness, swelling, pain, or small amounts of purulent discharge. As an antibiotic, erythromycin ointment effectively inhibits bacterial growth, reduces inflammatory responses, and helps relieve discomfort. Before application, the skin around the eyes should be cleaned.
Erythromycin ointment should not be used if the redness, swelling, and itching are due to allergies, viral infections, or dry eye syndrome. Allergic reactions typically involve significant itching without pain; viral infections may present with blisters; and dry eye syndrome often causes a dry, foreign-body sensation in the eyes. Since erythromycin ointment is ineffective against these non-bacterial causes, inappropriate use may disrupt the natural microbial balance of the periorbital skin, increase irritation, or delay proper treatment.
While waiting for medical evaluation, symptoms can be temporarily relieved by avoiding eye rubbing, maintaining good ocular hygiene, and applying cold compresses. Additionally, attention to personal hygiene can help reduce the risk of eye infections.