Can patients with bipolar disorder take bupropion hydrochloride sustained-release tablets?
Nov 24, 2025
Source: Cainiu Health
Dr. Zhang Baohua
Introduction
In general, whether patients with bipolar disorder can take bupropion hydrochloride sustained-release tablets should be determined based on the specific condition of the illness. If any discomfort occurs, prompt medical consultation is recommended. Proper lifestyle management is essential during treatment. Maintain a regular sleep schedule and avoid staying up late, which may disrupt emotional rhythms. Eat a light and balanced diet, and reduce intake of stimulating beverages such as coffee and alcohol.
Generally, whether patients with bipolar disorder can take bupropion hydrochloride sustained-release tablets depends on the specific clinical condition. If any discomfort occurs, it is recommended to seek medical advice promptly. The detailed analysis is as follows:
Patients currently in a depressive episode and without a history of manic or hypomanic episodes may be considered for this medication after physician evaluation. These patients primarily experience symptoms such as low mood and reduced energy, which the drug may help alleviate by regulating neurotransmitters. Before initiating treatment, it must be confirmed that the patient is in a stable phase of depression. The doctor will also consider factors such as age and underlying medical conditions to ensure that the benefits of the medication outweigh potential risks.
Patients experiencing manic or hypomanic episodes, or those with a history of frequent mixed episodes, should not take this medication. The drug may increase neural excitability, potentially triggering or worsening manic symptoms, leading to elevated mood, racing thoughts, and impulsive behaviors. Additionally, individuals who are allergic to the drug's components or have severe underlying conditions such as cardiovascular or cerebrovascular diseases or epilepsy should avoid using it to prevent serious adverse reactions.
Lifestyle management is essential during treatment. Maintain a regular sleep schedule and avoid staying up late, which can disrupt emotional rhythms. Eat a light, balanced diet and reduce intake of stimulants such as coffee and alcohol. Engage in moderate daily exercise, such as walking or yoga, to help stabilize mood. Proactively communicate your feelings with family and friends to avoid bearing psychological stress alone. If significant mood fluctuations or physical discomfort occur, seek immediate medical attention and report symptoms promptly so that the treatment plan can be adjusted as needed.
