Will mixing honey and coffee cause poisoning?
Generally, mixing honey and coffee does not usually cause poisoning. The detailed analysis is as follows:

Coffee primarily contains components such as caffeine and tannic acid, while honey consists mainly of fructose and glucose. These ingredients can stably coexist under normal drinking temperatures, neither producing toxic substances nor compromising each other's original nutritional properties. Moreover, the natural sweetness of honey can help neutralize the bitterness of coffee, making this a common and safe combination. As long as both ingredients are fresh and unspoiled, there is no need to worry about safety when consuming them together.
When consuming, it's important to control the amount of honey added to avoid excessive sugar intake, which may increase metabolic burden—especially for individuals with diabetes who should strictly limit their consumption. Coffee should not be too hot, as high temperatures can destroy the active components in honey and may irritate the oral and esophageal mucosa. It's best to avoid or minimize consumption on an empty stomach, particularly for those with weak gastrointestinal function, to prevent discomfort caused by caffeine irritating the gastric lining. Honey should be stored sealed in a cool place, and coffee should be kept dry to maintain quality and ensure safe consumption.