Should adenosylcobalamin tablets or methylcobalamin be used for tinnitus?

Nov 26, 2025 Source: Cainiu Health
Dr. Lu Cheng
Introduction
When tinnitus is associated with peripheral nerve damage of the ear or nutritional deficiency, adenosylcobalamin tablets or methylcobalamin may be selected as appropriate. Both are vitamin B12-related agents that can participate in nerve repair and metabolism, improving nerve function. For this type of neurogenic tinnitus, taking these medications as directed by a physician may alleviate symptoms and help reduce abnormal ear sounds.

Generally, if tinnitus is caused by peripheral nerve lesions, either adenosylcobalamin tablets or mecobalamin can be used. However, if the cause is non-neurological, the effectiveness of both agents is limited. If in doubt, it is recommended to seek medical advice promptly. Detailed analysis is as follows:

When tinnitus is associated with damage to the peripheral nerves of the ear or nutritional deficiencies, either adenosylcobalamin tablets or mecobalamin may be selected based on the specific situation. Both belong to the vitamin B12 class of drugs and can participate in nerve repair and metabolism, thereby improving nerve function. For this type of neurogenic tinnitus, taking these medications as prescribed may help alleviate symptoms and reduce abnormal sounds in the ears.

If tinnitus is caused by non-neurological factors such as otitis media, otosclerosis, or hypertension, using adenosylcobalamin or mecobalamin alone is generally ineffective. In such cases, treatment should first target the underlying condition—such as controlling inflammation or regulating blood pressure. Relying solely on neurotrophic drugs is unlikely to resolve the root problem, and inappropriate use may delay timely intervention for the primary disease.

Before using either medication, the cause of tinnitus must be clearly identified. The choice of drug and dosage should strictly follow medical guidance. If tinnitus does not improve after a period of medication, a timely follow-up visit is necessary to adjust the treatment plan, and self-administered long-term use should be avoided.

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