Which medication for chronic rhinitis is the most effective?

Commonly used medications for the treatment of chronic rhinitis include budesonide nasal spray, oxymetazoline hydrochloride nasal drops, loratadine tablets, montelukast sodium tablets, and physiological seawater nasal sprays. Detailed explanations are as follows:

1. Budesonide Nasal Spray: As a representative intranasal corticosteroid, it reduces inflammatory responses in the nasal mucosa and alleviates symptoms such as nasal congestion, itching, and runny nose. It is suitable for long-term control of chronic rhinitis. The medication should be used regularly according to prescribed courses, acting directly on the nasal mucosa to minimize recurrent inflammation. It is a fundamental drug commonly used in managing chronic rhinitis.

2. Oxymetazoline Nasal Drops: This belongs to nasal decongestants that rapidly constrict blood vessels in the nasal mucosa, effectively relieving nasal congestion. It is appropriate for short-term use only. It can be temporarily used when nasal blockage severely affects daily life. Prolonged use should be avoided to prevent drug-induced rhinitis. Strict adherence to recommended duration and dosage is essential.

3. Loratadine Tablets: A commonly used antihistamine, this drug is indicated when chronic rhinitis is associated with allergic factors. It helps reduce symptoms including nasal itching, sneezing, and clear watery discharge. Available in both oral and nasal formulations, the choice depends on symptom severity, helping to relieve allergy-related manifestations of rhinitis.

4. Montelukast Sodium Tablets: As a leukotriene receptor antagonist, it inhibits the release of inflammatory mediators, reducing nasal mucosal edema and inflammation. It is particularly suitable for patients with chronic rhinitis accompanied by asthma or allergic symptoms. By modulating inflammatory responses, it improves rhinitis symptoms and is often used in combination with other drugs to enhance therapeutic efficacy.

5. Physiological Seawater Nasal Spray: Although not a conventional medication, it effectively cleanses the nasal cavity by removing secretions and irritants, while maintaining moisture in the nasal mucosa. It assists in relieving symptoms such as nasal congestion and dryness. Suitable for daily use, it helps maintain a stable nasal environment, reduces triggers of inflammation, and complements other medications to improve overall treatment outcomes.

Medication selection should be based on the specific type and symptoms of chronic rhinitis, and must always be done under the guidance of a physician to avoid self-medication.