Should cephalosporin or amoxicillin be taken for acute pharyngitis?

Nov 27, 2025 Source: Cainiu Health
Dr. Ren Yi
Introduction
When acute pharyngitis is accompanied by fever, purulent discharge in the throat, and blood tests indicating elevated markers of bacterial infection, cephalosporins or amoxicillin may be required. Both medications target bacterial infections by inhibiting bacterial growth, helping to control inflammation and relieve symptoms such as sore throat and fever. However, the appropriate drug should be selected based on a doctor's assessment.

Generally, if acute pharyngitis is caused by a bacterial infection, cephalosporins or amoxicillin may be appropriate; however, if it is due to a viral infection, these two medications are ineffective. If in doubt, it is recommended to seek medical advice promptly. The detailed analysis is as follows:

When acute pharyngitis is accompanied by fever, pus in the throat, and blood tests indicating elevated markers of bacterial infection, treatment with cephalosporins or amoxicillin may be necessary. Both drugs target bacterial infections, inhibit bacterial growth, help control inflammation, and alleviate symptoms such as sore throat and fever. However, the appropriate medication should only be selected after evaluation by a physician.

If acute pharyngitis is caused by a viral infection—characterized by sore throat, cough, absence of obvious pus, and no signs of bacterial infection in blood tests—using cephalosporins or amoxicillin will not relieve symptoms and may increase the risk of drug side effects. In such cases, recovery typically relies on the body's own immune system, and the unnecessary use of antibiotics should be avoided.

During an episode of acute pharyngitis, it is important to drink plenty of warm water and avoid fatigue. Before taking any medication, always confirm whether there is a history of drug allergy. If symptoms do not improve or worsen after three days of medication, prompt re-evaluation and adjustment of the treatment plan are advised.

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