What medication should be used for a persistently non-healing sore inside the nose?
Nov 28, 2025
Source: Cainiu Health
Dr. Liu Wenmin
Introduction
The inside of the nose is ulcerated and not healing. Commonly used medications include erythromycin ointment, recombinant human epidermal growth factor gel, mupirocin ointment, compound menthol nasal drops, and Kangfuxin solution. Erythromycin ointment: an external antibacterial agent that inhibits bacterial growth, prevents and treats infections of the nasal mucosa, and promotes repair of damaged mucosal tissue.
Nasal sores that persist without healing can generally be treated with commonly used medications such as erythromycin ointment, recombinant human epidermal growth factor gel, mupirocin ointment, compound menthol nasal inhalant, and Kangfuxin solution. Specific details are as follows:
1. Erythromycin Ointment: This is a topical antibacterial agent that inhibits bacterial growth, prevents and treats infections of the nasal mucosa, and promotes the repair of damaged mucosal tissue. Apply a small amount gently to the affected area inside the nose, avoiding excessive application that may block the nasal passage. It is suitable for nasal ulcers caused by bacterial infection.
2. Recombinant Human Epidermal Growth Factor Gel: This product promotes regeneration of epithelial cells, accelerates healing of damaged nasal mucosa, and reduces scar formation. After cleaning the nasal cavity, apply an appropriate amount of the gel to the ulcerated area. It is ideal for severe mucosal damage or slow-healing conditions. Note that the gel should be stored refrigerated to maintain its efficacy.
3. Mupirocin Ointment: A topical antibiotic with strong antimicrobial activity, effective in treating nasal infections caused by Gram-positive cocci, and helps alleviate redness and swelling associated with ulcers. Apply evenly to the affected area. It is recommended for bacterial nasal ulcers that do not respond well to conventional antibacterial treatments.
4. Compound Menthol Nasal Inhalant: Contains menthol and camphor, which help moisturize the nasal mucosa, relieve dryness, clean nasal secretions and crusts, and reduce irritation at the site of ulceration. Suitable as adjunctive therapy for nasal ulcers caused by dryness or inflammation.
5. Kangfuxin Solution: Promotes blood circulation, nourishes yin, and supports tissue regeneration. It aids in mucosal repair and relieves pain from ulcers. Use a cotton swab to apply a small amount of the solution directly to the affected area. Suitable for nasal mucosal ulcers caused by various factors, especially chronic or recurrent cases that fail to heal.
Before applying any medication, wash your hands and clean the nasal cavity, and avoid picking the nose forcefully. If there is no improvement after one week of treatment, or if symptoms such as bleeding or increased pain occur, seek medical attention promptly.
