Do you need to take biologics for psoriasis for life?

Nov 29, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
If the patient's condition is mild, symptoms have stabilized and improved after treatment with biologics, and there has been a prolonged period without recurrence, the medication may be gradually tapered or discontinued under medical supervision, and long-term injections are not necessary. However, if the patient has severe disease, frequent relapses, or is prone to rebound symptoms after stopping the drug, long-term maintenance therapy with biologics may be required.

In general, biologic agents for psoriasis do not need to be administered for life. Some patients may require long-term maintenance therapy, but the treatment duration should be determined based on individual disease conditions. If there are concerns, it is recommended to consult a healthcare provider in advance. Detailed analysis is as follows:

If a patient has mild disease and achieves stable symptom relief after biologic treatment, with no recurrence over an extended period, the medication may be gradually tapered or discontinued under medical supervision, eliminating the need for long-term injections. Subsequent regular follow-up visits and lifestyle management can effectively control the condition and reduce the overall duration of drug use.

For patients with severe disease, frequent relapses, or those prone to rebound symptoms after stopping treatment, long-term use of biologics may be necessary to maintain disease control. In these cases, the medication helps continuously suppress inflammation and prevent worsening of symptoms that could impair quality of life. Regular injections and monitoring of bodily responses should be carried out strictly according to medical advice.

During treatment with biologic agents, it is essential to strictly follow medical instructions—do not discontinue or adjust dosage without guidance. Regular physical examinations are required to monitor potential adverse effects. If any changes in the condition occur, timely communication with the physician is necessary to adjust the treatment plan accordingly.

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