Is it effective to apply toothpaste on lip blisters?
Generally, whether applying toothpaste is effective for lip blisters depends on the specific cause of the blisters. If discomfort occurs, it is recommended to seek medical attention promptly. The details are as follows:

If the lip blisters are caused solely by mild internal heat or brief local friction resulting in superficial redness and swelling, applying toothpaste may provide temporary relief. The cooling ingredients in toothpaste can reduce the sensation of burning, and certain fluoride components may temporarily inhibit surface bacterial growth, reducing the likelihood of worsening inflammation. However, this relief is only temporary and does not address the underlying cause of the blisters.
However, if the lip blisters are caused by viral infections (such as cold sores), allergies, or infected skin breaks, applying toothpaste is ineffective and may even worsen discomfort. Ingredients in toothpaste such as fragrances and abrasives can irritate damaged mucous membranes and may clog pores at the affected site, impairing skin metabolism. Blisters caused by viral infections require targeted antiviral treatment, as toothpaste cannot inhibit viral replication.
When cleaning the lips, gently wipe with mild water, avoiding vigorous rubbing of the affected area. Drink plenty of water daily to stay hydrated and reduce dryness and discomfort of the lips. Limit consumption of spicy or excessively hot foods to avoid irritating the blistered area. Applying a non-irritating lip balm appropriately can help maintain lip moisture, reduce external irritation to the affected area, and support the recovery of lip skin.