What medication is used for pustular dermatophytosis?

Dec 01, 2025 Source: Cainiu Health

Dr. Liu Wenmin

Introduction

In general, commonly used medications for treating pustular tinea include bifonazole cream, terbinafine hydrochloride cream, miconazole nitrate cream, compound ketoconazole ointment, and itraconazole capsules (to be taken under medical supervision). Bifonazole cream is an antifungal medication that inhibits the synthesis of fungal cell membranes, disrupts fungal structures, and thereby eliminates the fungi causing pustular tinea.

Generally, commonly used medications for treating pustular tinea include bifonazole cream, terbinafine hydrochloride cream, miconazole nitrate cream, compound ketoconazole ointment, and itraconazole capsules (to be taken under medical supervision). Detailed analysis is as follows:

1. Bifonazole Cream: This is an antifungal topical medication that inhibits fungal cell membrane synthesis and disrupts the fungal structure, thereby killing the fungi responsible for pustular tinea and relieving symptoms such as skin redness, pustules, and itching. It is suitable for mild to moderate infections.

2. Terbinafine Hydrochloride Cream: It exerts antifungal effects by inhibiting fungal squalene epoxidase, thus preventing the formation of the fungal cell membrane. This helps rapidly reduce inflammatory responses in pustular tinea, promotes healing of pustules, and lowers the risk of recurrence.

3. Miconazole Nitrate Cream: It interferes with fungal cell membrane synthesis, rendering fungi inactive. Effective against various pathogenic fungi, it relieves itching and redness caused by pustular tinea and helps prevent the spread of pustules. It is suitable for localized topical treatment.

4. Compound Ketoconazole Ointment: Contains ketoconazole and clobetasol propionate. The former has antifungal properties, while the latter reduces inflammation. Their combined action targets both fungal infection and inflammatory response, quickly alleviating symptoms such as redness, pustules, and itching associated with pustular tinea.

5. Itraconazole Capsules (to be taken under medical supervision): An oral antifungal agent that works by inhibiting fungal cytochrome enzymes. It is indicated for extensive lesions or cases where topical treatments are ineffective. Must be taken according to a prescribed course to ensure therapeutic efficacy.

Prior to applying topical medications, the affected area should be cleaned, and application should be avoided on severely damaged skin. Oral medications must be used strictly under a doctor's guidance; self-adjusting dosage is not recommended. During treatment, keep the affected area dry and clean, and avoid scratching to prevent spreading the infection. If symptoms fail to improve or worsen after medication use, seek medical attention promptly to adjust the treatment plan.

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