What symptoms do family members have after being infected with syphilis from a female carrier?
Dec 03, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
Chancre: This is a common early symptom of syphilis, characterized by a firm, painless, non-itchy ulcer that typically appears at the site of infection, such as the genitals, lips, or mouth. Family members who come into contact with the infected area may develop similar ulcers at these sites. Lymphadenopathy: After the appearance of the chancre, lymph nodes near the infected area may become swollen.
After a woman with syphilis infects family members, the affected individuals typically develop symptoms such as hard chancre, swollen lymph nodes, skin and mucous membrane lesions, fever, and headache. The details are as follows:
1. Hard chancre: This is a common early sign of syphilis, appearing as a firm, painless, non-itchy ulcer usually located at the site of infection, such as the genitals or lips. Family members who come into contact with the infected areas of the patient may develop similar ulcers at these sites.
2. Swollen lymph nodes: Following the appearance of a hard chancre, nearby lymph nodes—such as those in the groin—may become enlarged. Initially, there might be redness, swelling, warmth, and pain; later, the nodes may adhere together and form larger ulcers.
3. Skin and mucous membrane lesions: Infected family members may develop red or reddish-brown papules or maculopapular rashes all over the body, including on the palms and soles, sometimes accompanied by mild itching. Mucosal lesions may also occur, such as white patches on the oral mucosa.
4. Fever: The *Treponema pallidum* bacterium may affect the body's temperature regulation center, causing fever. After infection, family members may experience low-grade or moderate fever.
5. Headache: As syphilis weakens the immune system, it increases susceptibility to infections and triggers inflammatory responses. Infected family members may develop systemic symptoms such as headache and fatigue.
To prevent the spread of syphilis, close contact with infected individuals should be avoided, and personal items that may come into contact with blood or bodily fluids—such as towels and razors—should not be shared. Anyone exhibiting suspicious symptoms should seek medical attention promptly, and once diagnosed, undergo standardized treatment and regular follow-up.
