Will taking Bacillus subtilis and Enterococcus faecalis granules before a nucleic acid test have any effect?

Dec 04, 2025 Source: Cainiu Health

Dr. Ren Yi

Introduction

In general, taking Bifidobacterium triple viable granules before nucleic acid testing usually does not directly affect the test results. If you experience any discomfort, it is recommended to seek medical attention promptly. Follow your doctor's instructions for medication, maintain regular dietary habits, and avoid raw, cold, or irritating foods to reduce intestinal burden. Practice good personal hygiene by washing hands frequently and keeping indoor areas well-ventilated to lower the risk of infection.

Under normal circumstances, taking Bacillus subtilis bivalent live bacterial granules before nucleic acid testing typically does not directly affect the test results. If discomfort occurs, it is recommended to seek medical attention promptly. The specific analysis is as follows:

Nucleic acid testing primarily identifies specific pathogen nucleic acid sequences in samples by using primers and probes that precisely bind to target fragments. Bacillus subtilis bivalent live bacterial granules contain live bacterial components that act on the intestinal tract to regulate microbial balance. The nucleic acid sequences of these bacteria have no homology with the target pathogen, so they do not cause cross-reactions with the test reagents, nor do they interfere with the extraction and amplification of the target nucleic acid. Therefore, they do not directly alter the test outcome. After ingestion, the live bacteria function only within the gastrointestinal tract and do not enter the respiratory system or bloodstream to affect the test sample; they also do not degrade or modify the nucleic acid of the target pathogen.

In daily life, medications should be taken as prescribed, with regular eating habits maintained, and consumption of raw or irritating foods avoided to reduce gastrointestinal burden. Good personal hygiene practices—such as frequent handwashing and keeping indoor areas well-ventilated—should be observed to lower infection risk. If gastrointestinal discomfort worsens or other unusual symptoms occur, prompt medical consultation is advised to ensure safe and scientifically sound medication use and health management.

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Can I get a nucleic acid test right after having a tooth pulled?

Whether one can undergo a nucleic acid test immediately after tooth extraction depends on the post-extraction condition. Patients who have no significant bleeding or swelling after the procedure may proceed with the test. However, those with large extraction wounds, persistent bleeding, or severe pain are advised to postpone testing. After tooth extraction, it is essential to strictly follow medical instructions and properly care for the wound, avoiding vigorous rinsing or chewing hard foods. If nucleic acid testing is necessary, individuals should inform the sampling personnel in advance about their recent tooth extraction.

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Does eating onions before taking a nucleic acid test have any effect?

In general, eating onions before a nucleic acid test will not affect the test results. However, consuming excessive amounts or having a sensitive mouth may cause discomfort and interfere with the sampling process. To ensure smooth sample collection, it is recommended to avoid eating heavily within one hour prior to testing, and to avoid irritants such as onions, garlic, chili peppers, alcohol, and chewing gum.

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Can I drink water or take medication before a nucleic acid test?

In general, drinking a small amount of water before a nucleic acid test usually does not affect the results, and routine medications can be taken as usual. However, consuming large amounts of water or taking certain special medications might interfere with sample collection or the testing process. To ensure the efficiency and accuracy of the nucleic acid test, it is recommended to avoid drinking large amounts of water, eating, or chewing gum within 30 minutes prior to testing. During sample collection, cooperate with healthcare personnel by tilting your head back and opening your mouth as instructed.

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Can I get a nucleic acid test after receiving the HPV 9-valent vaccine?

The function of the nine-valent vaccine is to stimulate the body to produce antibodies against human papillomavirus, thereby preventing related infections. Its components do not cross-react with the target pathogens of nucleic acid testing. Nucleic acid testing detects pathogens by amplifying specific nucleic acid sequences; the vaccine does not interfere with this testing process, nor does it cause false-positive or false-negative results.