Can receiving a COVID-19 vaccine cause aplastic anemia?

Dec 10, 2025 Source: Cainiu Health
Dr. Li Feng
Introduction
In general, receiving a COVID-19 vaccine does not cause aplastic anemia. After vaccination, ensure adequate sleep and avoid excessive fatigue to allow the body to recover stably. Maintain a balanced diet with sufficient protein and vitamin-rich foods to enhance your immune system. Pay attention to your physical condition; if you experience persistent fatigue, pale complexion, gum bleeding, or other abnormalities, seek medical advice promptly.

Under normal circumstances, receiving a COVID-19 vaccine does not cause aplastic anemia. The detailed analysis is as follows:

COVID-19 vaccines primarily work by activating the immune system to produce antibodies, and their components do not contain substances that damage bone marrow hematopoietic function. Aplastic anemia is mostly triggered by genetic factors, chemical toxins, or viral infections, leading to failure of bone marrow hematopoietic stem cell function. Current extensive clinical data show that reported cases following vaccination are extremely rare, and there is no clear evidence establishing a causal relationship between the vaccine and aplastic anemia, so excessive concern is unnecessary.

After vaccination, ensure adequate sleep and avoid overexertion to allow stable recovery of bodily functions. Maintain a balanced diet with sufficient protein and vitamin-rich foods to strengthen immunity. Monitor your health closely; if persistent fatigue, paleness, gum bleeding, or other unusual symptoms occur, seek professional medical evaluation promptly. Keep the injection site clean to prevent infection, allowing the body to complete its immune response in a safe environment.

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