How to Investigate the Causes of Infertility
May 30, 2022
Source: Cainiu Health
Dr. Lv Aiming
Introduction
There are numerous causes of infertility, including immunological factors, ovulatory disorders, tubal obstruction, endocrine imbalances, and poor semen quality. Blood tests can detect the presence of immune antibodies—such as anti-endometrial antibodies, anti-cardiolipin antibodies, and anti-sperm antibodies—as well as assess the six key endocrine hormones and AMH (anti-Müllerian hormone) to rule out conditions like premature ovarian insufficiency and hyperprolactinemia.
Most young men and women begin considering having children soon after marriage; however, if conception does not occur despite prolonged attempts at pregnancy, significant stress may ensue. So, how can the underlying causes of infertility be investigated?
How to Investigate the Causes of Infertility
Infertility has numerous potential causes, including immunological factors, ovulatory disorders, tubal obstruction, poor semen quality, and endocrine imbalances. Blood tests can detect the presence of immune antibodies—such as anti-endometrial antibodies, anti-cardiolipin antibodies, and anti-sperm antibodies—as well as assess six key endocrine parameters and anti-Müllerian hormone (AMH) levels to rule out conditions like premature ovarian insufficiency, hyperprolactinemia, and polycystic ovary syndrome (PCOS). Thyroid function tests help exclude thyroid hormone abnormalities. Transvaginal ultrasound is used to monitor ovulation and assess follicular development. Hysterosalpingography (HSG), performed after menstruation, evaluates tubal patency. Semen analysis in the male partner assesses sperm quality.
If infertility stems from congenital abnormalities, it may be untreatable. However, the majority of infertility cases are treatable, enabling patients to achieve successful pregnancy. Even in cases of male azoospermia, pregnancy may still be possible using donor sperm. Nevertheless, for patients with premature ovarian insufficiency, advanced maternal age, or severe intrauterine adhesions (e.g., Asherman’s syndrome), the absence of high-quality oocytes or a favorable endometrial environment for embryo implantation currently precludes effective clinical treatment. Thus, not all forms of infertility are curable.
In daily life, prioritize adequate rest, avoid frequent late-night activity, and ensure sufficient sleep. We hope this information proves helpful!
