What is Hemorrhagic Fever with Renal Syndrome (HFRS)?
Disease description:
A physical examination revealed hemorrhagic fever with renal syndrome (HFRS). I have symptoms including fever, generalized body aches, and hypotension. I am not very familiar with this disease—what exactly is hemorrhagic fever with renal syndrome?
Doctor's answer (1)
Dr. Zhao Xinju
Hemorrhagic Fever with Renal Syndrome (HFRS) is a naturally occurring zoonotic disease primarily caused by hantaviruses. Clinically, it manifests as fever, renal impairment, shock, and hemorrhage. HFRS can be classified into five types:
- **Mild type**: Characterized by relatively mild systemic toxic symptoms and minimal renal damage.
- **Moderate type**: The most common form, presenting with more pronounced systemic toxic symptoms.
- **Severe type**: Marked by severe systemic toxicity, shock, and significant renal impairment.
- **Critical type**: Features refractory shock and serious complications.
- **Atypical type**: Presents with positive specific antigens or antibodies in blood or urine, without typical clinical manifestations.
