Can hypothyroidism cause thyroid enlargement?

In patients with hypothyroidism, the thyroid gland may become enlarged. However, not all patients will develop this enlargement. Hypothyroidism is a systemic condition characterized by low metabolism, primarily due to insufficient hormone secretion or reduced hormone action. It is more common in women and can be classified according to the site of dysfunction as primary, central, or thyroid hormone resistance syndrome. Treatment options include surgical intervention or radioactive iodine therapy.