Is IgA vasculitis the same as IgA nephropathy?
Disease description:
A friend's father was diagnosed with IgA nephropathy. They want to know: Is IgA vasculitis the same as IgA nephropathy?
Doctor's answer (1)
Dr. Yang Tiesheng
IgA nephropathy is different from vasculitis. IgA nephropathy is the most common primary glomerular disease and ranks first as the cause of end-stage renal disease in China. It tends to worsen after upper respiratory tract infections and shows familial clustering. Its pathological hallmark is the deposition of large polymeric underglycosylated IgA1-specific immune complexes in the glomeruli. The main clinical manifestations include hematuria, proteinuria, and renal dysfunction.
