
Can testicular dysgenesis lead to azoospermia?
Disease description:
My younger brother is 36 years old this year and has poor testicular development. He hasn't had any children yet. Can poor testicular development lead to azoospermia?

Testicular dysgenesis may lead to azoospermia. The testes are the primary male reproductive organs responsible for sperm production. If they fail to develop properly, their spermatogenic function may be severely impaired. In severe cases, underdeveloped testes may produce insufficient sperm or even no sperm at all, resulting in azoospermia. Since azoospermia is a major cause of male infertility, individuals who suspect testicular dysgenesis should seek timely medical evaluation and follow their doctor's recommendations for treatment, in order to prevent azoospermia and maintain male reproductive health.