How to treat edema caused by lupus nephritis

The treatment of edema in lupus nephritis requires a comprehensive approach involving multiple measures, as follows: 1. Dietary adjustment: Low-salt and low-fluid diet, with daily salt intake less than 3 grams. Strict control of fluid intake is necessary, including porridge, soup, beverages, and fruits. 2. Medication therapy: Diuretics such as hydrochlorothiazide and furosemide may be used, possibly in combination with potassium-sparing diuretics like spironolactone to relieve edema. Glucocorticoids and immunosuppressive agents, such as prednisone, methylprednisolone, cyclosporine, and tacrolimus, can modulate the immune response and reduce kidney damage, thereby alleviating edema. 3. Other treatments: Prevention of infection, avoidance of nephrotoxic drugs, and ensuring adequate rest. For patients with severe edema unresponsive to diuretics, hemodialysis may be considered.