What should be done if Sjögren's syndrome is accompanied by cirrhosis?

Jul 02, 2024 Source: Cainiu Health
Disease description:

I have Sjögren's syndrome, and today during the examination, cirrhosis of the liver was also detected. What should I do if I have both Sjögren's syndrome and cirrhosis?

Doctor's answer (1)
Dr. Yang Ziqi
For patients with Sjögren's syndrome complicated by cirrhosis, treatment should comprehensively consider the conditions of both diseases: 1. For Sjögren's syndrome: Use artificial tears to relieve dry eyes, and sugar-free products or fluids to alleviate dry mouth. Immunosuppressants such as azathioprine may be used when necessary, along with glucocorticoids such as methylprednisolone (which should be gradually tapered). Attention should also be paid to oral hygiene and eye care. 2. For cirrhosis: Conduct antiviral or immunomodulatory therapy according to the underlying cause (e.g., viral hepatitis, autoimmune, etc.). Hepatoprotective medications such as ursodeoxycholic acid may be used to improve liver function. For complications such as ascites, measures such as diuretics and albumin supplementation may be implemented. 3. Comprehensive management: Adjust lifestyle habits, quit smoking and alcohol consumption, control diet, and ensure adequate rest. Regularly monitor disease progression and adjust treatment plans accordingly.