Colchicine's Mechanism of Action and Therapeutic Effects

Jul 11, 2024 Source: Cainiu Health
Disease description:

I have been experiencing frequent joint pain recently and was diagnosed with gout after visiting the hospital. My doctor prescribed colchicine. I would like to ask the doctor, what are the functions and benefits of colchicine?

Doctor's answer (1)
Dr. Yang Tiesheng
The functions and benefits of colchicine mainly include: 1. Treatment of acute gout: Colchicine is a classic medication for treating acute gouty arthritis, capable of rapidly alleviating severe pain and inflammatory responses during gout attacks. 2. Prevention of gout attacks: During non-acute phases, low-dose usage helps prevent recurrent gout attacks and reduces joint inflammation and pain. 3. Anti-inflammatory effects: It can inhibit the activity and migration of inflammatory cells (such as neutrophils) and decrease the release of inflammatory mediators, thereby reducing inflammatory responses. 4. Other effects: It may also have pharmacological effects such as anti-tumor activity and pain relief. Colchicine is a prescription drug; its use should follow medical advice, with strict dosage control to avoid side effects and adverse reactions.